"Lignocaine vs GTN Ointment for Postoperative Pain After Hemorrhoidectomy")

Recruiting now · Not applicable

Conditions studied: Hemorrhoid, Postoperative Pain

In brief

This study is being conducted at the Department of General Surgery, King Edward Medical University, Lahore, Pakistan. The purpose of the trial is to compare the effectiveness of topical Lignocaine ointment versus topical Glyceryl Trinitrate (GTN) ointment in reducing postoperative pain following hemorrhoidectomy. Patients undergoing hemorrhoidectomy will be randomly assigned to receive either Lignocaine ointment or GTN ointment applied locally after surgery. Pain relief will be assessed using a visual analog scale (VAS) at regular intervals during the postoperative period. The study aims to determine which ointment provides better pain control and improves patient comfort during recovery.

Key facts

Study ID

NCT07159334

Run by

King Edward Medical University

People needed

64

Starts

2025-08-02

Expected to finish

2025-12-01

Last updated by the study team

2025-09-08

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age between 18 - 60 years
• Both genders
• Grade III and IV hemorrhoids diagnosed on the basis of history and clinical examination by consultant Surgeon.(Grade III Hemorrhoid manually reduced by patient with finger and Grade IV is prolapsed)
• ASA (American society of Anesthesia) grades I, and II

You may not qualify if…

• Previously reported allergy or reaction to lignocaine and GTN
• Pregnancy or lactation
• Concomitant perianal pathology warranting surgery
• Cardiovascular disease
• Patient taking Nitrates or Calcium channel blocker

Where it is running

• King Edward Medical uUniveristy Mayo Hospital — Lahore, Punjab Province, Pakistan (enrolling)

Full record on ClinicalTrials.gov

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