Genicular Nerve Block for Knee Pain in the ED
Recruiting now · Not applicable
Conditions studied: Knee Pain
In brief
Patient with atraumatic knee pain without a large knee effusion on x-ray will be randomized to receive either a genicular nerve block (GNB) or standard of care in the emergency department.
Key facts
- Study ID
- NCT07158736
- Run by
- University of Pennsylvania
- People needed
- 34
- Starts
- 2025-08-06
- Expected to finish
- 2026-09-01
- Last updated by the study team
- 2026-02-12
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Atraumatic knee pain
- >17 years age
- X-ray of the knee obtained in the ED
- Initial pain score (numeric rating scale) 5-10
You may not qualify if…
- Fracture or dislocation on x-ray
- large knee joint effusion identified on x-ray
- allergy or contraindication to local anesthetics
- History of local anesthetic systemic toxicity after receiving local anesthetics
- Pregnancy
- Incarcerated
- History of knee replacement of affected knee
- Concern for septic joint
- Overlying cellulitis
- Hemodynamic instability
- Altered mental status or inability to consent for procedure.
Where it is running
- Hospital of the University of Pennsylvania — Philadelphia, Pennsylvania, United States (enrolling)
- Pennsylvania Hospital — Philadelphia, Pennsylvania, United States (enrolling)
- Pennsylvania Presbyterian Medical Center — Philadelphia, Pennsylvania, United States (enrolling)
- HUP Cedar — Philadelphia, Pennsylvania, United States (enrolling)
Full record on ClinicalTrials.gov
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