Effect of a Plant-Focused Diet on Nutritional Status in Malnourished Peritoneal Dialysis Patients

Recruiting now · Not applicable

Conditions studied: End Stage Renal Disease (ESRD), End Stage Kidney Disease (ESRD), Peritoneal Dialysis (PD), Malnourished

In brief

The goal of this clinical trial is to determine whether a plant-focused diet improves nutritional and health outcomes of malnourished adults undergoing peritoneal dialysis (PD). It will also learn about the safety of this diet in this population. The main questions it aims to answer are: 1. Does a plant-focused diet improve nutritional status compared to a standard kidney diet in PD patients? 2. What changes occur in anthropometric, biochemical, and dietary measures over 6 months? Researchers will compare the plant-focused diet to a standard-of-care renal diet to see which is more effective in improving nutrition in PD patients. Participants will: * Be randomly assigned to follow the plant-focused diet or the standard diet. * Be monitored for 6 months through in-person visits (aligned with their routine clinic appointments) and virtual check-ins via messages or calls. * Have their progress monitored for changes in outcomes such as nutrition, blood tests, kidney function, and quality of life.

Key facts

Study ID: NCT07157397
Run by: National University of Malaysia
People needed: 100
Starts: 2026-03-10
Expected to finish: 2027-03-31
Last updated by the study team: 2026-03-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Adult outpatients (>18 years old), attending HTCM PD clinic visits
Have undergone peritoneal dialysis for at least 6 months
Have a serum albumin level <40 g/L
Have a BMI of < 25 kg/m2
Have a malnutrition inflammation score (MIS) of mild, moderate or severe
Agreed to follow the dietary instructions based on the randomization assignment
Agreed to attend baseline visits and additional follow-up appointments at months 1, 3, and 6 post- randomization, either in person or via telehealth, and respond to monthly or more frequent phone calls

You may not qualify if…

Have been hospitalized for the past 3 months
Have ongoing infection/sepsis
Has undergone surgery in the past 6 months
Have high inflammatory diseases, malignancy, or cancer
Have dialysis adequacy of <1.2 Kt/V

Where it is running

Hospital Canselor Tuanku Muhriz UKM — Cheras, Kuala Lumpur, Malaysia (enrolling)

Full record on ClinicalTrials.gov

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