Phase 2b Study of EVO756 in Adults With Atopic Dermatitis

Running, not enrolling · Phase 2 · Has a placebo group

Conditions studied: Atoptic Dermatitis

In brief

This study will evaluate the efficacy and safety of different doses of EVO756 in adults with moderate to severe atopic dermatitis.

Key facts

Study ID

NCT07150845

Run by

Evommune, Inc.

People needed

120

Starts

2025-08-26

Expected to finish

2026-07-01

Last updated by the study team

2026-05-18

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Chronic AD that has been present for ≥6 months
• Validated-Investigator's Global Assessment score of ≥3
• EASI of ≥16
• BSA of AD involvement of ≥10%

You may not qualify if…

• Any clinically significant abnormality in laboratory evaluations, physical examinations, vital signs, or ECG at Screening
• Use of certain medications
• Presence of skin comorbidities or other condition(s) that may interfere with study assessments
• Significant AD flare, in the opinion of the Investigator, within 4 weeks prior to study entry

Where it is running

• Saguaro Dermatology — Phoenix, Arizona, United States
• Center for Dermatology Clinical Research — Fremont, California, United States
• Metropolis Dermatology - Downtown Los Angeles — Los Angeles, California, United States
• Skin and Beauty Center — Pasadena, California, United States
• Skin Care Research, LLC — Boca Raton, Florida, United States
• Driven Research, LLC — Coral Gables, Florida, United States
• Skin Care Research - Hollywood Dermatology — Hollywood, Florida, United States
• TrueBlue Clinical Research — Tampa, Florida, United States
• DS Research — Clarksville, Indiana, United States
• Equity Medical — Bowling Green, Kentucky, United States
• Aesthetic and Dermatology Center — Rockville, Maryland, United States
• Great Lakes Research Group, Inc. — Bay City, Michigan, United States
• Revival Research Institute, LLC — Troy, Michigan, United States
• Michigan Dermatology Institute — Waterford, Michigan, United States
• MediSearch Clinical Trials — Saint Joseph, Missouri, United States
• Empire Dermatology — East Syracuse, New York, United States
• Equity Medical — New York, New York, United States
• Skin Search of Rochester, Inc. — Rochester, New York, United States
• Wilmington Dermatology Center — Wilmington, North Carolina, United States
• DOCS Dermatology Clinical Research — Canal Winchester, Ohio, United States
• International Clinical Research - Murfreesboro — Murfreesboro, Tennessee, United States
• Stryde Research — Lewisville, Texas, United States
• Progressive Clinical Research — San Antonio, Texas, United States
• Jordan Valley Dermatology Center — South Jordan, Utah, United States
• Pacific Clinical Research Network (PCRN) - Christchurch — Christchurch Central City, Christchurch, New Zealand

Full record on ClinicalTrials.gov

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