Inflammatory Biomarkers as Predictors of PONV Following Pediatric Orchiopexy

Recruiting now

Conditions studied: Pediatric Anesthesia, Postoperative Nausea and Vomiting (PONV), Inflammatory Biomarkers

In brief

Orchiopexy is a common surgical procedure for the treatment of cryptorchidism in the pediatric population, with a high incidence of postoperative nausea and vomiting (PONV). Recent evidence suggests that systemic inflammation may contribute to PONV pathogenesis, and preoperative inflammatory biomarkers such as NLR, PLR, SII, MLR, and SIRI could serve as predictive indicators. This prospective observational study aims to evaluate the relationship between these biomarkers and PONV incidence in children undergoing orchiopexy.

Key facts

Study ID

NCT07148063

Run by

Diskapi Yildirim Beyazit Education and Research Hospital

People needed

170

Starts

2025-09-08

Expected to finish

2026-03-27

Last updated by the study team

2025-09-09

Who can join

Age: 1 and older, up to 8. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients aged between 1 and 8 years
• Patients with ASA physical status I-II
• Patients scheduled for elective orchiopexy
• Obtained written informed consent from parents/guardians

You may not qualify if…

• Patients younger than 1 year or older than 8 years
• Patients with ASA physical status III or higher
• Presence of acute infection signs
• History of previous nausea or vomiting

Where it is running

• Ankara Etlik City Hospital — Altındağ, Ankara, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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