No Sedation Versus Daily Interruption of Sedation in Chronic Obstructive Pulmonary Disease Mechanically Ventilated Patients- A Prospective Study

Recruiting now

Conditions studied: Chronic Obstructive Pulmonary Disease (COPD), Sedation and Analgesia

In brief

this study is to compare no-sedation versus daily interruption of sedation (DIS) in Chronic obstructive pulmonary disease (COPD) patients receiving mechanical ventilation upon the ventilator-free days.

Key facts

Study ID

NCT07146698

Run by

Benha University

People needed

60

Starts

2024-11-01

Expected to finish

2025-10-01

Last updated by the study team

2025-09-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients of both sex aged 18 years or older
• The study will include 60 patients divided into 2 equal groups
• Invasive mechanical ventilation
• Patients with COPD patients (post-bronchodilator FEV1/FVC< 70, and under follow through the department outpatient clinic) exacerbation admitted to the ICU and required invasive mechanical ventilation were recruited.

You may not qualify if…

• Allergy to sedative which will be used
• renal or hepatic impairment
• proven or suspected psychiatric or neurological impairment
• pregnancy

Where it is running

• Benha University Hospitals — Banhā, Qalyubia Governorate, Egypt (enrolling)

Full record on ClinicalTrials.gov

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