Post-stroke Pain tAN-fMRI

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Post Stroke Pain

In brief

The purpose of this study is to explore whether 4 weeks of at-home transcutaneous auricular neurostimulation (tAN) can reduce chronic pain after a stroke. Investigators will recruit up to 24 participants with chronic post-stroke upper extremity pain. The goal is to determine if there is a pain reduction after ear stimulation.

Key facts

Study ID

NCT07144436

Run by

Medical University of South Carolina

People needed

24

Starts

2026-01-08

Expected to finish

2027-06-30

Last updated by the study team

2026-02-04

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18-80
• Have the capacity and ability to provide one's own consent in English and sign the informed consent document.
• Ischemic or hemorrhagic stroke that occurred at least 6 months prior

You may not qualify if…

• Primary intracerebral hematoma or subarachnoid hemorrhage
• Documented history of dementia
• Documented history of uncontrolled depression or psychiatric disorder
• Uncontrolled hypertension despite treatment, specifically SBP (Systolic Blood Pressure) / DBP (Diastolic Blood Pressure) >=180/100mmHg
• Contraindicated for MRI scanning
• Pregnancy

Where it is running

• 30 Bee Street — Charleston, South Carolina, United States (enrolling)
• Medical University of South Carolia — Charleston, South Carolina, United States

Full record on ClinicalTrials.gov

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