Parasternal Intercostal Muscle Thickening as an Additive Weaning Criterion

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Critically Ill

In brief

Increased days of MV are not without hazards, including barotraumas and ventilator-associated pneumonia. Similarly, premature separation of MV is associated with increased mortality secondary to adverse cardiorespiratory events. Therefore, the time of weaning should be wisely evaluated. There is growing evidence concerning respiratory muscles dysfunction that contributes to difficulty or prolonged liberation from MV.

Key facts

Study ID

NCT07143695

Run by

Cairo University

People needed

200

Starts

2025-09-01

Expected to finish

2026-08-31

Last updated by the study team

2025-09-08

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• critically ill patient mechanically ventilated for 24 hours or more first spontaneous breathing trial

You may not qualify if…

• patient refusal difficult ultrasound views tracheostomized patient neuromuscular disorders

Where it is running

• Cairo University — Cairo, Giza Governorate, Egypt (enrolling)

Full record on ClinicalTrials.gov

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