Effect of the Intelligent Lipid Management Decision-support System on 1-year LDL-C Target Achievement in Ischemic Stroke or TIA Patients Under Evolocumab Treatment in China
Recruiting now · Not applicable
Conditions studied: Ischemic Stroke, Transient Ischemic Attack (TIA)
In brief
This study will conduct a cluster randomized controlled trial to Evaluate whether the Intelligent Lipid Management Decision-support System can increase the proportion of patients 1-year target achievement (\<1.8 mmol/L) in acute ischemic stroke or TIA patients under Evolocumab treatment within 12 months post-intervention.
Key facts
- Study ID
- NCT07143149
- Run by
- Beijing Tiantan Hospital
- People needed
- 4000
- Starts
- 2025-11-03
- Expected to finish
- 2028-03-31
- Last updated by the study team
- 2026-01-02
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age≥18 years as of the screening date;
- Patients with non-cardioembolic ischemic stroke or TIA within 3 months prior to the screening date;
- Prescribed Evolocumab at physician's discretion;
- Signed informed consent.
You may not qualify if…
- Intracranial hemorrhagic diseases: such as cerebral hemorrhage, subarachnoid hemorrhage, etc.;
- Patients confirmed by baseline head CT or MRI to have hemorrhage or other pathological brain diseases, such as vascular malformations, tumors, abscesses, or other common non-ischemic brain diseases (such as multiple sclerosis);
- Silent cerebral infarction without signs and symptoms;
- Participation in a clinical trial of another drug or device in the past 3 months or ongoing at the time of the screening date;
- Any prior use of Evolocumab or other PCSK9 inhibitor treatments within the past 6 months prior to the screening date;
- Life expectancy <12 months or unable to complete the research for other reasons as of the screening date;
- Inability to understand and/or follow research procedures due to mental, cognitive, or emotional disorders;
- Refusal to participate in the enrollment survey.
Where it is running
- Beijing Tiantan Hospital — Beijing, China (enrolling)
Full record on ClinicalTrials.gov
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