Clinical Evaluation of With or Without Internal Limiting Membrane Peeling for Idiopathic Epiretinal Membrane Surgery: A Randomized Controlled Trial
Recruiting now · Not applicable
Conditions studied: Idiopathic Epiretinal Membranes
In brief
Idiopathic epiretinal membrane (ERM) is an age-related degenerative retinal condition. One of the primary treatment approaches is vitrectomy combined with epiretinal membrane peeling. However, whether to concurrently perform internal limiting membrane (ILM) peeling remains clinically controversial. Therefore, this study aims to compare the efficacy and safety of performing versus omitting ILM peeling during idiopathic ERM surgery.
Key facts
- Study ID
- NCT07142785
- Run by
- Second Affiliated Hospital, Zhejiang University, School of Medicine
- People needed
- 96
- Starts
- 2025-09-01
- Expected to finish
- 2028-06-30
- Last updated by the study team
- 2025-08-27
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients aged >18 years presenting to our hospital within the study period.
- Patients diagnosed with idiopathic epiretinal membrane (ERM) based on examination.
- Patients with best-corrected visual acuity (BCVA) ≤ 0.6 or the presence of metamorphopsia.
You may not qualify if…
- Patients with secondary ERM identified during preoperative evaluation (e.g., secondary to retinal vein occlusion).
- Patients with concomitant ocular diseases affecting the macula, such as macular degeneration, macular schisis, or macular atrophy.
- Patients with a history of ocular trauma or previous ocular surgery (except for cataract surgery).
- Patients with severe systemic diseases contraindicated for surgery.
- Patients with poor compliance or concomitant psychiatric disorders.
- Patients who participated in other clinical trials during the follow-up period or who were lost to follow-up.
Where it is running
- Eye Center of the Second Affiliated Hospital of Zhejiang University — Hangzhou, Zhejiang, China (enrolling)
Full record on ClinicalTrials.gov
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