Diagnostic Interest of Bone Tomoscintigraphy in the Search for Cervical Pseudarthrosis
Recruiting now · Not applicable
Conditions studied: Cervical Pseudarthrosis
In brief
Cervical pseudarthrosis is a classic complication and a challenge for challenge for spine surgeons. The rate of pseudarthrosis can range from 3 to 15%, and depend greatly on the patient, the approach the number of levels operated on. Although some patients remain asymptomatic, most require revision surgery instability, cervical or radicular pain. Diagnosis of cervical pseudarthrosis remains difficult. The clinical presentation is non-specific, and there is no consensus on the imaging imaging. Radiographic evaluation lacks sensitivity. The dynamic images require prior calibration and anatomical landmarks difficult to visualize. Angle measurement lacks reproducibility and sensitivity. CT scans, currently considered the gold standard as the gold standard, provides valuable morphological data but does not provide information on the functional nature of bone bridges the functional nature of bone bridges and apparent consolidation, particularly incomplete. At the same time, functional imaging using bone scintigraphy has been historically limited by lack of spatial resolution, absence of anatomical and radiation attenuation for deep structures.The advent of hybrid imaging makes it possible to these limitations. Recently, the 6 to 16 scanners fitted to gamma cameras enable a detailed study correlations between functional and anatomical data. Interpretation criteria remain unestablished, however, and only one study reports the use of hydric bone imaging in the study of cervical pseudarthrosis. All patients were positive on scintigraphy. However, given the absence of "healthy" patients and the small number of patients the diagnostic value of bone scintigraphy in this indication.
Key facts
- Study ID
- NCT07140432
- Run by
- GCS Ramsay Santé pour l'Enseignement et la Recherche
- People needed
- 100
- Starts
- 2024-12-31
- Expected to finish
- 2027-02-28
- Last updated by the study team
- 2026-07-16
Who can join
Age: 21 and older, up to 99. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients over 21 years of age
- Patients who have undergone cervical arthrodesis and are being treated at Clinique de la Sauvegarde or Clinique Convert
- Patients with a NDI clinical score at 1 year greater than 5
- Patient affiliated to/ or beneficiary of a Social Security scheme as definied by the law
You may not qualify if…
- Patients whose clinical condition requires rapid treatment that can't wait for examinations to be carried out
- Pregnancy and breastfeeding
- Protected person (curatorship, guardianship, safeguard of justice)
- History of hypersensitivity to the active substance ( sodium oxidronate) or to any of its constituents
Where it is running
- Clinique Convert ( INA) — Bourg-en-Bresse, France (enrolling)
Full record on ClinicalTrials.gov
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