Axillary Radiotherapy or Axillary Lymph Node Dissection in Patients With Clinically Node- Positive Breast Cancer Undergoing Upfront Tailored Axillary Surgery
Recruiting now · Not applicable
Conditions studied: Breast Cancer
In brief
This trial is to investigate if in patients with clinically node positive breast cancer undergoing upfront surgery, treatment with TAS and ART is superior to ALND in terms of arm-related Quality of Life (QoL) and occurrence of lymphedema two years after randomization.
Key facts
- Study ID
- NCT07140172
- Run by
- University Hospital, Basel, Switzerland
- People needed
- 1060
- Starts
- 2026-01-01
- Expected to finish
- 2037-12-01
- Last updated by the study team
- 2026-08-07
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Centro di Senologia della Svizzera Italiana — Lugano, Switzerland (enrolling)
- Bethesda Hospital Basel — Pratteln, Switzerland (enrolling)
- Spital Thurgau — Frauenfeld, Switzerland (enrolling)
- Kantonsspital Luzern — Lucerne, Switzerland (enrolling)
- Hôpital Neuchâtelois — Neuchâtel, Switzerland (enrolling)
- MUI - Univ. Klinik f. Frauenheilkunde Innsbruck — Innsbruck, Austria (enrolling)
- Kantonsspital Baden — Baden, Switzerland (enrolling)
- Graubünden Cantonal Hospital — Chur, Switzerland (enrolling)
- Hôpitaux Universitaires de Genève — Geneva, Switzerland (enrolling)
- Hirslandenklinik St. Anna — Lucerne, Switzerland (enrolling)
- Fox Chase Cancer Center — Philadelphia, Pennsylvania, United States (enrolling)
- University Hospital Heidelberg, Women's Clinic — Heidelberg, Germany (enrolling)
- Brustzentrum Heidelberg Klinik St. Elisabeth GmbH — Heidelberg, Germany (enrolling)
- Breast Center Osnabrück — Osnabrück, Germany (enrolling)
- Ordensklinikum Linz — Linz, Austria (enrolling)
- Pauls Stradiņš Clinical University Hospital — Riga, Latvia (enrolling)
- Breast Surgery Service, University Hospital Basel — Basel, Switzerland (enrolling)
- Clinique des Grangettes — Chêne-Bougeries, Switzerland (enrolling)
- Medical University Vienna, Department of Surgery — Vienna, Austria (enrolling)
- KH Dornbirn — Dornbirn, Austria (enrolling)
- CIUSSS du Centre Ouest-de-l 'Ile-de-Montréal — Montreal, Canada (enrolling)
- Clinique de Genolier — Genolier, Switzerland (enrolling)
- LKH Feldkirch — Feldkirch, Austria (enrolling)
- University Hospital Galway — Galway, Ireland (enrolling)
- Kantonsspital St. Gallen — Sankt Gallen, Switzerland (enrolling)
Full record on ClinicalTrials.gov
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