Induction of Cross-protective Antibodies for Serogroup 33 by Pneumococcal Conjugate Vaccines

Recruiting now · Phase 4

Conditions studied: Vaccine, Pneumococcal Disease

In brief

The goal of this study is to learn whether different types of vaccines to prevent bacterial infections are able to effectively create antibodies that defend against certain types of bacteria. We will give two different types of vaccine and evaluate the effectiveness of antibodies produced by each vaccine in killing bacteria.

Key facts

Study ID

NCT07135453

Run by

University of Alabama at Birmingham

People needed

70

Starts

2026-07-01

Expected to finish

2027-08-01

Last updated by the study team

2026-07-09

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy adult

You may not qualify if…

• No prior history of pneumococcal vaccination
• No immunosuppressing medications or chronic diseases that affect immune function

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States (enrolling)

Full record on ClinicalTrials.gov

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