Vaped Phenanthrene

Starting soon · Not applicable

Conditions studied: Former Smoker, Non-Smoker

In brief

Some people who used to smoke cigarettes continue to be at higher risk of developing lung cancer, even years after quitting. This study will look to see if a specific chemical, phenanthrene, is broken down in the lungs of former smokers through more harmful pathways than never-smokers. If former smokers break down chemicals that enter their lungs through more harmful pathways this might be putting them at higher risk for developing lung cancer even though they quit smoking. This information may help find better ways to prevent or treat cancer in the future. This study is under an IND, but the drug is not being studied; instead, it is being used as a marker for drug metabolism.

Key facts

Study ID

NCT07134426

Run by

University of Minnesota

People needed

100

Starts

2026-08-14

Expected to finish

2028-06-30

Last updated by the study team

2026-08-05

Who can join

Age: 21 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• > 21 years of age
• In good physical \& mental health
• In stable physical \& mental health
• Have tried vaping
• Former daily cigarette smokers who quit 1-20 year ago
• Non-smokers who have not used tobacco or nicotine products

You may not qualify if…

• Has any respiratory disease (ex - asthma, COPD, etc...)
• Has/had high blood pressure
• Has/had liver disease
• Has/had cancer
• Has experience negative effects when vaped previously
• Pregnant or nursing

Where it is running

• University of Minnesota — Minneapolis, Minnesota, United States

Full record on ClinicalTrials.gov

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