Evaluation by Clinical and Hand Ultrasound in Carpal Tunnel Syndrome
Recruiting now
Conditions studied: Carpal Tunnel Syndrome (CTS), Carpal Tunnel Surgery
In brief
Carpal Tunnel Syndrome (CTS) is a common condition where pressure on the median nerve in the wrist causes pain, numbness, and weakness in the hand. Surgery to release the carpal tunnel is often performed to relieve these symptoms. This study will evaluate the changes in the median nerve after surgery and how these changes relate to symptom improvement. Investigators will use ultrasound imaging to measure the nerve size before and at three and six months after surgery. Patients will also complete questionnaires about their symptoms and hand function, and undergo tests to assess strength and sensation. The investigator's goal is to determine whether changes observed on ultrasound are associated with the rate of patient recovery. This may help doctors better monitor healing and improve care for people with CTS.
Key facts
- Study ID
- NCT07134361
- Run by
- University of Sao Paulo General Hospital
- People needed
- 106
- Starts
- 2025-06-25
- Expected to finish
- 2028-12-31
- Last updated by the study team
- 2025-08-28
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Clinical diagnosis of primary carpal tunnel syndrome (CTS), confirmed by characteristic symptoms, physical examination findings, and a cross-sectional area superior to 10 mm² in the ultrasonography baseline.
- Indication for open carpal tunnel release as part of routine clinical care.
You may not qualify if…
- Secondary CTS due to inflammatory arthritis, prior wrist trauma, or space-occupying lesions.
- History of previous carpal tunnel release in the affected hand.
- Concomitant peripheral neuropathies (e.g., diabetic polyneuropathy) or cervical radiculopathy
- Inability to undergo ultrasound assessment
Where it is running
- Instituto de Ortopedia e Traumatologia do Hospital das Clínicas da FMUSP — São Paulo, São Paulo, Brazil (enrolling)
Full record on ClinicalTrials.gov
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