Transcranial Photobiomodulation in Anxiety Disorders

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Symptoms of Anxiety

In brief

The investigators have previously shown that safe, non-invasive methods of brain stimulation such as the administration of transcranial infrared light can result in improvements to cognition and emotion. The investigators hypothesize that transcranial photobiomodulation (tPBM) can be used in conjunction with attention bias assessment and modification to reduce anxiety symptoms in individuals with sub-clinical anxiety.

Key facts

Study ID

NCT07133893

Run by

Francisco Gonzalez-Lima, PhD

People needed

280

Starts

2025-09-01

Expected to finish

2028-09-01

Last updated by the study team

2026-05-14

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 18 years of age and older
• State-Trait Anxiety Index (STAI) questionnaire score between 40-59 (indicates moderate sub-clinical anxiety)
• Patient Health Questionnaire (PHQ-9) score between 1-9 (indicates minimal to mild sub-clinical depression)

You may not qualify if…

• STAI score less than 40 or greater than 59
• PHQ-9 score greater than 9
• Medication instability (i.e., medication change within 6 weeks)
• Indicated suicidal ideation
• Currently receiving tPBM treatment
• Current pregnancy

Where it is running

• The University of Texas at Austin — Austin, Texas, United States (enrolling)

Full record on ClinicalTrials.gov

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