Real-World Cohort Study of Cardiopulmonary Function in Chinese Patients With Cardiovascular Disease: CPET Evaluation and Five-Year Prognostic Follow-Up Based on a Multicenter Structured Data Platform

Enrolling by invitation

Conditions studied: MACE, Cardiac Death, Unplanned Repeat Revascularization, Cardiac Rehospitalization, Non-fatal Myocardial Infarction, Stroke

In brief

The goal of this observational study is to observe the characteristics of cardiopulmonary exercise testing (CPET) parameters in patients across different cardiovascular diseases and to evaluate the predictive value of multiparameter cardiopulmonary indices for 5-year major adverse cardiovascular events (MACE).

Key facts

Study ID

NCT07130968

Run by

Guangdong Provincial People's Hospital

People needed

200000

Starts

2025-02-01

Expected to finish

2035-12-30

Last updated by the study team

2026-04-29

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age: 18-80 years,
• Ability to comprehend and provide written informed consent.

You may not qualify if…

• Comorbid severe conditions (e.g., recent acute myocardial infarction, unstable angina, uncontrolled arrhythmias, severe aortic coarctation or descending aortic aneurysm, acute myocarditis or pericarditis, acute congestive heart failure, acute respiratory failure, resting oxygen saturation <93%, recent arterial or pulmonary embolism, pulmonary edema).
• Conditions potentially exacerbated by exercise (e.g., acute cardiac insufficiency, exercise-induced asthma, epilepsy).
• Physical disability due to musculoskeletal or neuromuscular disorders.
• Pregnancy or lactation.
• Patients deemed unsuitable for participation by the investigator.

Where it is running

• Guangdong Provincial People's Hospital — Guangzhou, Guangdong, China

Full record on ClinicalTrials.gov

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