Incentives and Long-Acting Injectable Adherence After Involuntary Hospitalization

Enrolling by invitation · Not applicable

Conditions studied: Schizophrenia Disorder, Schizoaffective Disorder, Bipolar Disorder (BD), Substance Use Disorder (SUD)

In brief

This study is a randomized controlled trial evaluating the impact of financial incentives on medication adherence among individuals with schizophrenia, schizoaffective disorder, or bipolar disorder and/or co-occurring substance use disorder who are recently discharged from involuntary hospitalization or are at high risk of future involuntary hospitalization. Participants will be randomized to receive financial incentives for adherence to long-acting injectable medications or to a control group.

Key facts

Study ID

NCT07130500

Run by

Stanford University

People needed

1000

Starts

2026-03-09

Expected to finish

2030-03-01

Last updated by the study team

2026-03-27

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of schizophrenia, schizoaffective disorder, and/or bipolar disorder
• Recent (within 12 months) involuntary hospitalization or high risk of future hospitalization
• Eligible for medication (antipsychotic or SUD-related) with an LAI formulation
• Allegheny County, PA resident
• Receiving or assigned to treatment at clinics participating in this study

You may not qualify if…

• Lack of injectable formulation for prescribed medication
• Aged under 18 or 65 or older

Where it is running

• Pittsburgh Mercy — Pittsburgh, Pennsylvania, United States
• UPMC Franklin Building — Pittsburgh, Pennsylvania, United States
• UPMC Bellefield Towers — Pittsburgh, Pennsylvania, United States
• UPMC Oxford Building — Pittsburgh, Pennsylvania, United States
• UPMC Western Psychiatric Hospital — Pittsburgh, Pennsylvania, United States

Full record on ClinicalTrials.gov

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