Neutrophil to Lymphocyte Ratio in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Recruiting now

Conditions studied: Chronic Obstructive Pulmonary Disease Exacerbation

In brief

Chronic obstructive pulmonary disease (COPD) stands as one of the leading causes of mortality worldwide. Acute exacerbations of COPD (AECOPD) lead to rapid respiratory function decline and worsened disease status. Despite recent studies, the ability of the neutrophil-to-lymphocyte ratio (NLR) to predict outcomes in patients with COPD remains controversial. It remains controversial whether NLR can predict clinical outcomes in hospitalized patients with AECOPD. Therefore, this study was conducted to investigate the predictive value of NLR for severity, adverse outcomes in hospitalized patients with AECOPD, and predicting treatment response in patients with AECOPD

Key facts

Study ID

NCT07125352

Run by

Ain Shams University

People needed

190

Starts

2025-05-20

Expected to finish

2026-03-01

Last updated by the study team

2025-08-15

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients aged 18 and above, Patients who will be admitted at the Chest department, Ain-Shams University Hospitals, diagnosed with AECOPD based on the Global Initiative for Chronic Obstructive Lung Disease 2024 criteria

You may not qualify if…

• Patients who refused treatment.
• COPD patients with Malignancy, hematological disorders

Where it is running

• Ain Shams University — Cairo, Abbasyea, Egypt (enrolling)

Full record on ClinicalTrials.gov

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