Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences

Starting soon · Phase 3

Conditions studied: Gingival Inflammation, Dental Caries

In brief

Objectives: To evaluate the effectiveness of toothpaste tablets when compared to conventional dentifrices in removing plaque. Methods: 50 participants are randomized into two groups: Denttabs toothpaste tablets (T) and Colgate's Cavity Protection toothpaste (P). Both groups utilize their assigned dentifrice for 6 weeks. A pre and post-assessment measures the Gingival Index (GI) and Plaque Index (PI) and Decayed, Missing and Filled Teeth (DMFT). A questionnaire on the use of the product is distributed at the end of the study.

Key facts

Study ID

NCT07124533

Run by

Loma Linda University

People needed

50

Starts

2026-12-01

Expected to finish

2026-12-01

Last updated by the study team

2026-07-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Subjects are 18 years or older;
• Subjects who will comply with study protocol;
• Subjects who can read and understand the consent form;
• Subjects available during the study period;
• Subjects have more than 20 teeth.

You may not qualify if…

• Subjects under the age of 18.

Where it is running

• Loma Linda University Health — Loma Linda, California, United States
• Loma Linda University — Loma Linda, California, United States

Full record on ClinicalTrials.gov

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