Transcutaneous Auricular Vagus Nerve Stimulation on Post-Herpetic Neuralgia

Recruiting now · Not applicable

Conditions studied: Post Herpetic Neuralgia (PHN)

In brief

The purpose of this study is to evaluate the therapeutic efficacy of transcutaneous auricular vagus nerve stimulation (taVNS) in the treatment of patients with post-herpetic neuralgia (PHN). Participants will receive taVNS in addition to standard care. The study aims to determine whether taVNS can provide significant pain relief and improve quality of life in PHN patients.

Key facts

Study ID

NCT07123987

Run by

Mohamed Hosny Ismail Easa

People needed

34

Starts

2025-09-07

Expected to finish

2026-09-09

Last updated by the study team

2026-03-18

Who can join

Age: 35 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults aged 35-65 years diagnosed with PHN. Persistent pain for at least 3 months after herpes zoster infection. Only patients who sign the informed consent form will be included.

You may not qualify if…

• Contraindications to taVNS such as:
• pregnancy;
• active implants (e.g., pacemakers, cochlear implants) or brain shunts;
• previous neurological or psychiatric diagnoses;
• history of addiction or substance abuse;
• history of trauma and/or brain surgery;
• cardiac disease;
• acute or chronic use of medications and/or illicit drugs;
• susceptibility to headaches and seizures. Severe cognitive impairment. Other chronic pain conditions.

Where it is running

• Faculty of Physical Therapy - Cairo University — Cairo, Giza Governorate, Egypt (enrolling)

Full record on ClinicalTrials.gov

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