A Trial of SHR-7782 for Treatment of Advanced Malignant Tumors

Recruiting now · Phase 1

Conditions studied: Advanced Malignancy

In brief

The main objective of this study is to evaluate the effectiveness and safety of SHR-7782 for participants with advanced malignant cancer.

Key facts

Study ID

NCT07123129

Run by

Suzhou Suncadia Biopharmaceuticals Co., Ltd.

People needed

200

Starts

2025-08-28

Expected to finish

2027-12-01

Last updated by the study team

2026-01-30

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Participate in the study voluntarily, sign the informed consent form.
• Subjects were able to provide primary or metastatic cancer samples.
• At least one measurable lesion (RECIST version 1.1).
• ECOG 0\~1.
• With adequate organ functions.
• Expected survival time ≥ 12 weeks.

You may not qualify if…

• With untreated brain metastasis or active central nervous system tumor metastases.
• Imaging shows that the tumor invades large blood vessels or has unclear boundaries with blood vessels.
• Patients with other malignant tumors in the past or at the same time.
• Patients with clinical symptoms, uncontrolled, or moderate or above pleural effusion, pericardial effusion, or peritoneal effusion.
• Patients with a history of interstitial pneumonia or interstitial lung disease or non-infectious pneumonia requiring steroid treatment.
• With poorly controlled or severe cardiovascular disease.
• Bleeding events of NCI-CTCAE v5.0 grade ≥ 2 occurred within 1 month before the first medication.
• Subjects who had a serious infection within 1 month before the first medication.
• History of immunodeficiency.
• Known allergy to any component of the SHR-7782 product.
• According to the researcher's judgment, there are other factors that may affect the research results or cause the research to be terminated midway.

Where it is running

• Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College — Beijing, Beijing Municipality, China (enrolling)
• Zhejiang Cancer Hospital — Hangzhou, Zhejiang, China (enrolling)

Full record on ClinicalTrials.gov

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