Definitive Radiation Therapy for Inoperable Breast Cancer

Recruiting now · Not applicable

Conditions studied: Breast Cancer, Breast Adenocarcinoma

In brief

The purpose of this study is to find out if adding radiation therapy to routine medications for breast cancer helps in reducing and preventing the cancer from getting worse. Patients with a locally advanced breast cancer who cannot, or do not want to, undergo surgery are eligible to participate. Participation in this study does not prevent you from undergoing surgery in the future.

Key facts

Study ID

NCT07122713

Run by

Alexander Stessin

People needed

30

Starts

2025-12-08

Expected to finish

2033-12-30

Last updated by the study team

2025-12-17

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Biopsy proven invasive carcinoma of the breast, either lobular, ductal and/or no special type
• T1-T4, N0-2, M0-1 invasive breast carcinoma by radiological or clinical criteria
• Cancer is deemed unresectable, or the patient is a poor surgical candidate as determined following evaluation by a surgeon, or patient declines surgery.
• Life expectancy > 6 months
• Negative pregnancy test at the time of start of treatment in any female of reproductive age

You may not qualify if…

• Concurrent systemic therapy (except for endocrine therapy, HER2-targeted therapy, or immunotherapy which are permitted)
• Prior radiation to ipsilateral breast or regional nodes
• Inability to receive study treatment planning and treatment secondary to body habitus

Where it is running

• Stony Brook University Cancer Center — Stony Brook, New York, United States (enrolling)

Full record on ClinicalTrials.gov

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