Home Blood Transfusions

Recruiting now · Not applicable

Conditions studied: Hematologic Malignancy, Myelodysplastic Syndromes, Acute Myeloid Leukemia, Transfusion Dependent Cytopenias

In brief

This is a pilot single arm study to evaluate the feasibility and acceptability of a home blood transfusion program. Patients will be enrolled with hematologic malignancies and other bone marrow failure syndromes who are transfusion dependent and interested in a home blood transfusion program. Participants enrolled in the study will receive 1-5 units of blood products at home. Data on barriers to administration will be recorded. Surveys and qualitative interviews will be completed to better understand acceptability of the program.

Key facts

Study ID

NCT07121140

Run by

Thomas Jefferson University

People needed

30

Starts

2025-06-03

Expected to finish

2027-06-01

Last updated by the study team

2025-12-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Individuals must meet all of the following inclusion criteria in order to be eligible to participate in the study:
• Provide signed and dated informed consent form Willing to comply with all study procedures and be available for the duration of the study
• Male or female, over the age of 18
• Must meet definition of transfusion dependence (require at least 2 blood product transfusions over a 28-day period)
• Receive their cancer care at SKCCC
• Have a history of blood product transfusions and NO history of transfusion reactions,
• Live within a 30-mile range of the Center City SKCCC location.
• Must be willing to allow people into the home

You may not qualify if…

• An individual who meets any of the following criteria will be excluded from participation in this study:
• Patients who have a history of a transfusion reaction
• Heart failure as defined by AHA stage C or NYHA Class II-IV
• Non-English or Spanish speaking
• Are unhoused
• Are incarcerated
• Have poor venous access
• Diagnosis of Solid Tumor malignancy
• Women who are pregnant

Where it is running

• Thomas Jefferson University Hospital — Philadelphia, Pennsylvania, United States (enrolling)

Full record on ClinicalTrials.gov

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