PPI in Weaning Prediction

Recruiting now

Conditions studied: Perfusion Index, Weaning of Mechanical Ventilation, ICU

In brief

The aim of this study is to evaluate the predictive role of the Peripheral Perfusion Index (PPI) in forecasting extubation success during the weaning process in intensive care unit (ICU) patients. The study will investigate the ability of PPI to predict extubation failure by comparing it with traditional weaning criteria, including the Rapid Shallow Breathing Index (RSBI), PaO₂/FiO₂ ratio, and respiratory rate.

Key facts

Study ID

NCT07120672

Run by

Gaziosmanpasa Research and Education Hospital

People needed

100

Starts

2025-05-08

Expected to finish

2025-08-30

Last updated by the study team

2025-08-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients who have been on mechanical ventilation for at least 48 hours
• Patients over 18 years of age who are planned to undergo extubation following a spontaneous breathing trial (SBT)
• Patients or their legal representatives who provide informed consent to participate in the study

You may not qualify if…

• Patients for whom extubation is not planned due to hemodynamic instability
• Patients with peripheral vascular disease or a history of hand surgery
• Patients who die or cannot be followed up during the study period

Where it is running

• Gaziosmanpaşa Training and Research Hospital — Istanbul, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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