Personality Traits as a Variable in the Recovery of Patients With Acquired Brain Injury
Recruiting now
Conditions studied: Ictus, Severe Acquired Brain Injury, sABI
In brief
This study aims to evaluate the potential effects of premorbid personality on the short- and long-term global cognitive recovery in patients with severe acquired brain injury (sABI) or stroke. The secondary aims are to assess the effects of premorbid personality on the sort- and long-term recovery in autonomy (disability), cognitive functions, psycho-behavioral functioning, motor skills, and social participation. Evaluate the incidence of premorbid personality alterations. Investigate personality changes 12-18 months after the neurological event.
Key facts
- Study ID
- NCT07119827
- Run by
- Universita di Verona
- People needed
- 250
- Starts
- 2025-05-01
- Expected to finish
- 2028-05-01
- Last updated by the study team
- 2026-07-02
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- diagnosis of one of the following two conditions:
- Severe Acquired Brain Injury (sABI) of traumatic or non-traumatic etiology; the term sABI includes acute brain injuries of traumatic or non-traumatic origin (vascular, infectious, metabolic, or anoxic), in which the patient initially presents with a coma state (Glasgow Coma Scale - GCS less than 8) and simultaneously exhibits motor, sensory, cognitive, and/or behavioral impairments.
- Ischemic or hemorrhagic stroke without features of Severe Acquired Brain Injury (sABI) (Glasgow Coma Scale [GCS] score ≥ 8 and no alteration of consciousness).
- Time from injury between:
- 7 and 90 days for Severe Acquired Brain Injury (sABI) patients
- 3 and 30 days for stroke patients
- Level of Cognitive Functioning (LCF) score ≥ 6 for sABI patients
- Signed informed consent for study participation
- Presence of a support family member (caregiver) able to assist with completing the personality questionnaire (HEXACO Adjective Scale, HAS)
You may not qualify if…
- Pre-existing neurological pathology
- Severe aphasia or severe inattention that precludes administration of the tests required by the protocol, as identified during cognitive screening.
- Patients with a language barrier due to insufficient proficiency in Italian.
- Particularly vulnerable populations:
- The following patients will be excluded from the study: patients in emergency situations.
Where it is running
- Sezione medicina fisica e riabilitativa dipartimento di neuroscienze, verona — Verona, VR, Italy (enrolling)
Full record on ClinicalTrials.gov
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