Memory Deterioration in Alzheimer Disease

Recruiting now

Conditions studied: Alzheimer Disease, Neurodegenerative Diseases, Magnetic Resonance Imaging, Memory Impairment

In brief

Semantic AD

Key facts

Study ID

NCT07118137

Run by

Norwegian University of Science and Technology

People needed

30

Starts

2023-10-15

Expected to finish

2027-12-31

Last updated by the study team

2025-08-12

Who can join

Age: 55 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Confirmed diagnosis based on current ICD criteria for AD or MCI .
• >55years.
• Norwegian native speaker
• Lives at home and not in a health institution

You may not qualify if…

• Patients with severe cognitive impairment that prevents assessment with the selected modalities (planned cut-off: CDR > 2).
• Presence of brain tumors.
• History of traumatic brain injury.
• History of cranial surgery.
• Contraindications to the selected imaging modalities (e.g., 7T MRI or EEG).
• Diagnosis of other neurodegenerative diseases such as Parkinson's disease or ALS.
• 7T MRI contraindications:
• Large tattoos close to the head region, permanent makeup or unremoveable piercings
• Certain models of pacemakers (if pacemaker implantet, MRI physicist at 7T-lab will be conferred)
• Implantet metal in body (clips, stents, prothesis, skrews, plates, teeth etc.)

Where it is running

• Norwegian University of Sciene and Technology / Norges teknisk-naturvitenskapelige universitet (NTNU) — Trondheim, Trønderlag, Norway (enrolling)

Full record on ClinicalTrials.gov

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