A Pilot Study to Examine the Efficacy of Internet-Delivered Skills Training in Affective and Interpersonal Regulation (i-STAIR) for Individuals With Adverse Childhood Experiences and Subsyndromal Depression

Recruiting now · Not applicable

Conditions studied: Subthreshold Depression

In brief

The present study aims to pilot internet-delivered Skills Training in Affective and Interpersonal Regulation (i-STAIR) as a transdiagnostic emotion dysregulation intervention to prevent progression to depression in individuals with adverse childhood experiences (ACEs) and subsyndromal depression. The aims of the study are: (i) to examine the effectiveness of i-STAIR on emotion dysregulation, interpersonal skills, depressive and PTSD symptoms at post-intervention i.e. on completion of the intervention (8 weeks); (ii) to examine if gains were maintained at 3 month post- intervention follow-up.

Key facts

Study ID

NCT07118072

Run by

Institute of Mental Health, Singapore

People needed

150

Starts

2025-10-31

Expected to finish

2028-12-01

Last updated by the study team

2026-02-27

Who can join

Age: 21 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Exposed to mild, moderate or severe adverse childhood experiences (ACEs)
• Screened positive for subsyndromal depression
• Singapore citizens or permanent residents (PRs)
• Aged 21 years to 65 years
• Able to speak and understand English
• Willing and able to undergo intervention and assessment online

You may not qualify if…

• Currently diagnosed with any mental disorder diagnoses;
• Experience cognitive impairment as determined by attending physician
• Have received or currently receiving dialectical behavior therapy (DBT) due to similarities with i-STAIR
• Female participants who are pregnant

Where it is running

• Institute of Mental Health — Singapore, Singapore (enrolling)

Full record on ClinicalTrials.gov

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