Cost Effective Air Filtration Intervention in Low-Income Housing to Reduce Asthma Morbidity
Recruiting now · Not applicable · Has a placebo group
Conditions studied: Asthma Attack, Lung Function, Airway Inflammation
In brief
This project will investigate the effectiveness of HEPA air cleaners in reducing indoor air pollution and improving asthma morbidity in children living in East Harlem, New York City (NYC). The study will be conducted over a 2-year period. Columbia University and Little Sisters of the Assumption Family Health Service (LSAFHS) will conduct an intervention study to evaluate the efficacy of using a cost-effective high-capacity high efficiency particulate air (HEPA) filter air cleaner to reduce airborne particulate matter (PM) in the homes of children with asthma and to reduce their asthma morbidity. The study will take place in East Harlem, a low-income neighborhood with high asthma prevalence. It will build on findings from prior Housing and Urban Development Lead and Healthy Homes Technical Studies (HUD LHHTS)-funded research, the experience of LSAFHS installing air cleaners in the homes of asthmatic children, and recent findings demonstrating the effectiveness of home air cleaners in reducing asthma morbidity. The investigators hypothesize that the cost-effective single air cleaner will substantially reduce PM exposure in the homes of asthmatic children and reduce airway inflammation and asthma morbidity. This study will use cutting-edge air sampling technology to continuously quantify and characterize indoor air pollutants in the home for one year, verify and incentivize compliance, and conduct repeated exhaled nitric oxide and pulmonary function tests before and throughout the year after the intervention. This cost-effective intervention can be easily and quickly implemented in homes in low-income, urban communities and easily transferred between homes if families move.
Key facts
- Study ID
- NCT07116460
- Run by
- Columbia University
- People needed
- 55
- Starts
- 2026-01-30
- Expected to finish
- 2028-04-01
- Last updated by the study team
- 2026-06-02
Who can join
Age: 7 and older, up to 18. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age 7-18 years
- Asthma symptoms in the past 4 weeks
- Resident in lower-income housing in NYC Northern Manhattan and South Bronx
You may not qualify if…
- Inability to successfully perform spirometry maneuver or FeNO test
- Family planning to move in the next year
Where it is running
- Columbia University Irving Medical Center — New York, New York, United States (enrolling)
Full record on ClinicalTrials.gov
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