Bromelain for Post-surgery Facial Swelling

Recruiting now · Not applicable

Conditions studied: Malocclusion

In brief

The goal of this clinical trial is to learn if Bromelain Supplement works to decrease the amount of swelling or the amount of time swelling is present following jaw surgery. It will also learn about the safety of Bromelain supplement. The main questions it aims to answer are: Does Bromelain decrease facial swelling following orthognathic, or jaw, surgery? Does Bromelain supplement decrease the amount of time that patients are swollen following orthognathic, or jaw, surgery? Participants will: Take Bromelain supplement once daily for 9 days total. Take 2 days before surgery and 7 days following surgery. Keep a log of when the bromelain supplement is taken as well as another other medications. Visit the clinic with pre and post surgical protocol

Key facts

Study ID

NCT07115212

Run by

Mohamed Bazina

People needed

200

Starts

2025-09-08

Expected to finish

2028-05-01

Last updated by the study team

2026-06-05

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• undergoing orthognathic surgery

You may not qualify if…

• craniofacial anomalies
• incomplete patient data
• systemic disease that could affect healing
• allergy to latex or pineapple
• under 18 years of age
• non english speaking

Where it is running

• University of Kentucky — Lexington, Kentucky, United States (enrolling)

Full record on ClinicalTrials.gov

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