Electroacupuncture and rTMS for Post-Stroke Motor Recovery

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Stroke

In brief

This study aims to evaluate the combined efficacy of repetitive Transcranial Magnetic Stimulation (rTMS) and Electroacupuncture (EA) in improving motor function recovery post-stroke, compared to rTMS combined with sham EA. Participants will receive either active EA or sham EA alongside standard rTMS treatment. Outcomes will be assessed using standardized clinical scales and neuroimaging techniques to explore underlying neuroplasticity mechanisms.

Key facts

Study ID

NCT07113990

Run by

Jing Tao

People needed

180

Starts

2025-08-27

Expected to finish

2027-12-31

Last updated by the study team

2025-09-05

Who can join

Age: 40 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosed with stroke confirmed by neuroimaging (CT/MRI).
• First-ever stroke, unilateral hemispheric lesion, related to motor dysfunction.
• Age between 40 and 75 years.
• Duration from stroke onset between 2 weeks and 6 months.
• Brunnstrom stage II-IV.
• Right-handed.
• Able to understand instructions and voluntarily provide written informed consent.

You may not qualify if…

• History of epilepsy or familial epilepsy.
• Motor dysfunction due to non-vascular causes (e.g., tumor, trauma).
• Severe aphasia or cognitive impairment (MoCA < 18).
• Severe systemic complications (e.g., severe organ dysfunction, deep vein thrombosis).
• Presence of metallic implants or contraindications for MRI.
• Severe anxiety (HAMA > 7) or depression (HAMD > 8).
• Severe spasticity (modified Ashworth ≥ 2).
• Fear or intolerance of TMS or electroacupuncture.
• Pregnancy, breastfeeding, or concurrent participation in other clinical trials affecting outcomes.

Where it is running

• Fuzhou University Affiliated Provincial Hospital — Fuzhou, Fujian, China (enrolling)
• Fujian Provincial People's Hospital — Fuzhou, Fujian, China
• Wenzhou Hospital of Traditional Chinese Medicine — Wenzhou, Zhejiang, China

Full record on ClinicalTrials.gov

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