Adaptation of Written Exposure Therapy in Substance Treatment

Completed · Not applicable

Conditions studied: Posttraumatic Stress Disorder, Substance Use Disorders

In brief

The purpose of this pilot non-randomized, uncontrolled clinical trial is to test the feasibility and efficacy of written exposure therapy (WET) for posttraumatic stress disorder (PTSD) as adapted for use within the context of residential substance use disorder (SUD) treatment. All participants meet criteria for PTSD and are in a short term residential SUD treatment program (target residential treatment duration = 28 days) regardless of the research. The main question the study aims to answer is: 1) Is the delivery of adapted WET feasible and acceptable in short term residential SUD treatment for individuals with severe SUD?

Key facts

Study ID

NCT07108608

Run by

Potomac Health Foundations

People needed

26

Starts

2025-11-21

Expected to finish

2026-06-22

Last updated by the study team

2026-06-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Enrolled in residential SUD treatment at MTC
• Meet criteria for PTSD based on the Clinician-Administered PTSD Scale for DSM-5
• Be 18 years of age or older
• Have sufficient memory of the index trauma to write about it
• Be English speaking.

You may not qualify if…

• Inability to give informed consent for any reason (e.g., cognitive impairment)
• Presence of acute psychosis or suicidality that would interfere with study participation
• planning to leave residential treatment before WEST could realistically be completed as determined by the investigator

Where it is running

• Maryland Treatment Centers — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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