Prosthetic Joint Infection : Lessons From Deceased Patients in Critical Care.

Recruiting now

Conditions studied: Osteoarticular Infections, Intensive Care Patients, Prosthetic Joint Infection

In brief

This is an observational, retrospective, multicenter study based on the use of demographic, clinical and biological data from deceased patients admitted between 2018 and 2022 to critical care with a principal or associated diagnosis of joint prosthesis infection. Data from this study will be combined with that from the OASIS study (APHP241174/ ID-RCB: 2024-A01769-38) concerning osteoarticular sepsis on prosthetic material in critical care of living patients. The aim of this study is to improve our knowledge of the profile, care trajectories and outcomes of patients hospitalized in critical care in the context of osteoarticular material sepsis. The results of the study could help identify at-risk populations and improve management strategies for patients with osteoarticular sepsis.

Key facts

Study ID: NCT07107685
Run by: Assistance Publique - Hôpitaux de Paris
People needed: 150
Starts: 2025-09-24
Expected to finish: 2026-09-24
Last updated by the study team: 2026-06-01

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Patient aged 18 years or older.
Hospitalization in critical care (intensive care unit or continuing care unit) between 2018 and 2022, lasting at least 48 hours, with a prosthetic joint infection (hip, knee, or shoulder prosthesis infection) as the primary or associated diagnosis.
Deceased patient who had not refused data processing.

You may not qualify if…

Infection involving osteosynthesis material
Infection involving spinal instrumentation
Patient with multiple infected prostheses
Recurrence of prosthetic infection with the same microorganism as a previous episode
Patient under legal protection
Pregnant or breastfeeding patient
Patient deprived of liberty

Where it is running

Hôpital Lariboisière — Paris, France, France (enrolling)

Full record on ClinicalTrials.gov

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