A Study to Assess Safety and Efficacy of Surgical Implant of RNDP-001 in Patients With Idiopathic Parkinson's Disease

Running, not enrolling · Phase 1/Phase 2

Conditions studied: Idiopathic Parkinson´s Disease, Parkinson's Disease

In brief

This clinical trial is designed to test the safety and tolerability of the study intervention, RNDP-001, which will be implanted into the brain of study participants during a surgical procedure.

Key facts

Study ID

NCT07106021

Run by

Kenai Therapeutics

People needed

12

Starts

2025-07-17

Expected to finish

2031-06-01

Last updated by the study team

2026-07-27

Who can join

Age: 45 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of idiopathic Parkinson's disease consistent with the Movement Disorders Society Clinical Criteria
• Age 45 to 75
• Medically stable to undergo a surgical procedure

You may not qualify if…

• Known Parkinson's disease gene mutation or variant
• Previous infusion therapy or surgery for Parkinson's disease
• History of allergic reaction or intolerance to an immunotherapeutic agent
• Contraindication to MRI
• Clinically significant medical conditions likely to interfere with the surgical procedure or study assessments

Where it is running

• University of Arizona — Tucson, Arizona, United States
• Keck Medical Center of University of Southern California — Los Angeles, California, United States
• The Ohio State University Wexner Medical Center — Columbus, Ohio, United States

Full record on ClinicalTrials.gov

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