Total Intravenous Anesthesia in Patients Undergoing Craniotomy

Recruiting now · Not applicable

Conditions studied: Anesthesia

In brief

Craniotomy presents true anesthetic challenges, mainly due to the need to optimize cerebral perfusion, facilitate brain relaxation, achieve rapid emergence for neurologic assessment, and minimize perioperative complications.

Key facts

Study ID

NCT07105618

Run by

Zagazig University

People needed

108

Starts

2025-08-10

Expected to finish

2027-04-01

Last updated by the study team

2026-05-06

Who can join

Age: 21 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patient acceptance.
• Physical status: American Society of Anesthesiologists Physical Status (ASA) 1\& II.
• Body mass index ≤ 30 kg/m2.
• Type of operation: elective craniotomy for brain tumor resection.
• Duration of surgery: within 4 hours.

You may not qualify if…

• Patient with hemodynamic instability or anticipated postoperative mechanical ventilation.
• Patients with a known history of allergy to the study drugs.
• Advanced hepatic, renal, cardiovascular, and neurologic diseases.
• Patients with chronic opioid use.

Where it is running

• Zagazig university hospital — Zagazig, Egypt (enrolling)

Full record on ClinicalTrials.gov

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