Visual Plasticity Following Brain Lesions
Recruiting now · Not applicable · Has a placebo group
Conditions studied: Visual Field Defect, Stroke, Hemianopia, Quadrantanopia, Cortical Blindness, Brain Tumor, Traumatic Brain Injury, Visual Field Defect, Peripheral
In brief
The VIBRANT (Vision Improvement through Behavioral Rehabilitation And Neuroplasticity Training) study is a prospective, double-blind, crossover design (within-subject) in participants with homonymous hemianopia-a type of visual field loss resulting from damage to the post-chiasmatic visual pathways. It aims to investigate whether transcranial random noise stimulation (tRNS) combined with perceptual learning-based training has potential for improving visual impairments.
Key facts
- Study ID
- NCT07105358
- Run by
- Georgetown University
- People needed
- 30
- Starts
- 2025-07-17
- Expected to finish
- 2028-06-30
- Last updated by the study team
- 2025-08-05
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- At least 18 years of age.
- Capable of providing informed consent and complying with study procedures.
- Unilateral or bilateral focal brain damage causing loss of vision.
- At least three months post-stroke or traumatic brain injury, or a stable brain tumor within the past year.
You may not qualify if…
- Severe CNS diseases or disorders unrelated to the focal lesion, which could interfere with study results.
- Severe mental health challenges that could interfere with study results, or current or recent (within the past 6 months) drug or alcohol abuse or addiction as defined by DSM-5.
- Vision loss resulting from ocular disease or disorder.
- B. Healthy volunteers (age-matched controls):
- Inclusion Criteria:
- At least 18 years of age.
- Capable of providing informed consent and complying with study procedures.
- Exclusion Criteria:
- Any CNS diseases or psychiatric disorders (e.g., epilepsy, schizophrenia) that would interfere with study results.
- Previous head injury.
- Present or past (within past 6 months) drug or alcohol abuse or addiction based on DSM-5.
Where it is running
- Georgetown University Medical Center — Washington D.C., District of Columbia, United States (enrolling)
Full record on ClinicalTrials.gov
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