Parathyroidectomy and Mobility Study
Recruiting now
Conditions studied: Hyperparathyroidism, Parathyroid, Mobility
In brief
This study evaluates whether surgical removal of the parathyroid gland (parathyroidectomy) improves physical function and mobility in older adults with primary hyperparathyroidism (PHPT). PHPT, a common endocrine disorder in older adults, is associated with reduced muscle strength, mobility, and quality of life. This prospective observational study will enroll up to 80 participants aged 60 and older undergoing parathyroidectomy at UF Health. Participants will complete physical performance tests, wear an Actigraph device to assess physical activity, and provide blood samples for biomarker analysis at pre- and post-operative time points. The goal is to characterize changes in physical function and activity following surgery and to identify biomarkers that may predict mobility improvements. Findings will help inform future larger-scale studies and could expand surgical indications for PHPT in older adults.
Key facts
- Study ID
- NCT07103876
- Run by
- University of Florida
- People needed
- 80
- Starts
- 2025-08-15
- Expected to finish
- 2027-03-31
- Last updated by the study team
- 2025-09-29
Who can join
Age: 60 and older, up to 100. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Clinical and Translational Research Building — Gainesville, Florida, United States (enrolling)
Full record on ClinicalTrials.gov
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