Effect of a Microprocessor-controlled Prosthetic Knee Joint on K2 Level Ambulators

Starting soon · Not applicable

Conditions studied: Transfemoral Amputation, Limb Loss, Limb Absence

In brief

Microprocessor-controlled knees (MPKs) automatically adjust resistance or damping in the joint to improve swing- and/or stance-phase control as appropriate for the prosthesis user during gait. The purpose of this proposed investigation is to determine if there are substantial physical and psychological benefits to fitting lower functioning Veteran ambulators having transfemoral amputations with an MPK compared with a nonmicroprocessor-controlled knee (NMPK). Using a repeated-measures, cross-sectional experimental design, approximately 20 Veterans with unilateral, transfemoral amputations will be evaluated on two separate occasions at the Jesse Brown VA Medical Center or the Edward Hines, Jr. VA Hospital, first with their conventional NMPK and then again after a 2-month accommodation period with the College Park Icon MPK.

Key facts

Study ID

NCT07103798

Run by

VA Office of Research and Development

People needed

20

Starts

2026-07-01

Expected to finish

2028-06-30

Last updated by the study team

2026-05-08

Who can join

Age: 45 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Unilateral, transfemoral amputation (any etiology).
• Age from 45-85 years.
• Residual limb length classified as standard (i.e., medium) to long.
• Prosthesis user for at least 1 year prior to enrolling in the study.
• K2-level classification while using their NMPK.
• Good sensation on their residual limb.
• Good skin integrity upon visual inspection.
• Presents with good socket fit based upon a standard assessment by the study prosthetist.

You may not qualify if…

• Bilateral leg amputations.
• Individuals with a knee disarticulation.

Where it is running

• Jesse Brown VA Medical Center, Chicago, IL — Chicago, Illinois, United States
• Edward Hines Jr. VA Hospital, Hines, IL — Hines, Illinois, United States

Full record on ClinicalTrials.gov

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