Intracervical Vasopressin
Recruiting now · Phase 4 · Has a placebo group
Conditions studied: Retained Products of Conception
In brief
This randomized study looks at whether using a medicine injected into the cervix of the uterus (intracervical), called vasopressin, helps to achieve better removal of retained products of conception (RPOC). RPOC means that after a pregnancy has ended (through miscarriage, abortion, or delivery), some parts of the pregnancy tissue, usually from the placenta or fetus, have stayed in the uterus. A hysteroscopic removal of RPOC is one type of treatment. This is a surgical procedure where a doctor uses a small camera attached to a thin tube (called a hysteroscope) to look inside the uterus. The main goal of the study is : • To add to the existing research through this study to see if the injection of intracervical vasopressin leads to improved completion rates of hysteroscopic management of RPOC. Participants will: • would be randomized to receive either vasopressin intracervical injection or a placebo injection (non-active saline) during your procedure. Information from the procedure will be collected from the participant's medical record.
Key facts
- Study ID
- NCT07102615
- Run by
- Prisma Health-Upstate
- People needed
- 50
- Starts
- 2025-10-30
- Expected to finish
- 2026-12-01
- Last updated by the study team
- 2025-11-04
Who can join
Age: 18 and older, up to 51. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Women
- Aged 18-51
- Undergoing surgical management for retained products of conception, postpartum retained products of conception or 1st trimester missed or incomplete abortion
You may not qualify if…
- Hemodynamic instability
- Active hemorrhage- soaking pad/hour
- Allergy to vasopressin
- Concern for intrauterine arteriovenous malformation
- Inability to consent
Where it is running
- The OB/GYN Center — Greenville, South Carolina, United States (enrolling)
Full record on ClinicalTrials.gov
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