Chronic Exercise With Overdressing

Completed · Not applicable

Conditions studied: Heat Acclimation and Thermotolerance

In brief

The purpose of this study is to determine if five training sessions of exercise with overdressing can induce heat acclimation.

Key facts

Study ID

NCT07099872

Run by

United States Army Research Institute of Environmental Medicine

People needed

13

Starts

2024-10-28

Expected to finish

2025-05-05

Last updated by the study team

2025-08-01

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Females must be premenopausal.
• Body mass index 18.5-33.0 kg m-2.
• In good health as determined by the Office of Medical Support \& Oversight (OMSO) General Medical Clearance.
• Performs aerobic exercise at least 2 times per week and capable of running 2 miles in under 17:00 (8:30 minute mile pace).
• Willing to abstain from exercise and alcoholic beverages for 24 hrs before each study visit.
• Willing to abstain from caffeine for 12 hrs prior to all study visits.
• Willing to abstain from food for 2 hrs prior to all study visits.
• Willing to abstain from nicotine/tobacco for at least 8 hrs prior to all study visits.
• Have supervisor approval if permanent party military or a federal employee at U.S. Army Natick Soldier System Center.

You may not qualify if…

• Frequent hot bath or sauna users (e.g., more than three times a week for the past month).
• Females who are pregnant or planning to become pregnant during the study.
• Taking dietary supplements, prescriptions, or over the counter medication, other than a contraceptive (unless approved by OMSO \& PI).
• Abnormal blood count during OMSO medical screening (For example: hemoglobin (Hb) outside of the typical normal values reported by LabCorp in accordance with OMSO (Normal [Hb] Males = 12.6-17.7 g/dL; Females = 11.1-15.9 g/dL) or hematocrit (Hct) outside of the normal ranges (Normal Hct Males = 37.5-51.0%; Females = 34.0-46.6%) levels, presence of abnormal blood chemicals (hemoglobin S or sickle cell traits).
• Any history of pulmonary, cardiovascular, or renal disease (unless approved by OMSO \& PI).
• Uncontrolled asthma.
• Current or recent respiratory tract or sinus infections (< 2 weeks prior).
• History of heat stroke or orthostatic intolerance.
• Diagnosed and/or treated for fluid/electrolyte imbalance within the last 30 days.
• History of obstructive disease of the gastrointestinal tract including (but not limited to) diverticulosis, diverticulitis and inflammatory bowel disease, peptic ulcer disease, Crohn's disease, ulcerative colitis.
• Scheduled MRI during testing.
• Allergies to adhesives (e.g., medical tape).

Where it is running

• US Army Research Institute of Environmental Medicine — Natick, Massachusetts, United States

Full record on ClinicalTrials.gov

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