A Study for Cerebral Open Flow Microperfusion

Starting soon · Not applicable

Conditions studied: Glioma, Glioblastoma

In brief

The purpose of this study is to evaluate the safety and feasibility of intra-operative microperfusion during a planned neurosurgical resection of diseased brain parenchyma, including either an epileptic focus requiring temporal lobectomy or a glioma. Devices used for microperfusion are Joanneum Research cerebral open flow microperfusion (OFM) catheters, push and pull tubing, and MPP102-II pump.

Key facts

Study ID

NCT07089758

Run by

Mayo Clinic

People needed

6

Starts

2026-10-01

Expected to finish

2028-10-01

Last updated by the study team

2026-03-23

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• ECOG performance status (PS) 0, 1 or 2.
• Clinical and radiographic evidence diagnosis of glioma, or a prior diagnosis of glioma (suspected WHO grade II-IV), OR clinical evidence of epileptic foci requiring a temporal lobectomy.
• Clinical indication for resection as part of routine clinical care, with plan for this to be performed at Mayo Clinic (Rochester, MN).
• Able and willing to provide informed consent either signed by themselves or a legally authorized representative.

You may not qualify if…

• Vulnerable populations: pregnant women, prisoners or the mentally handicapped.
• Patients who are not appropriate candidates for surgery due to current or past medical history or uncontrolled concurrent illness.
• Patients whom the surgeon deems to be at increased risk of adverse effects from the study.

Where it is running

• Mayo Clinic in Rochester — Rochester, Minnesota, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.