The Effectiveness of Dexmedetomidine as an Adjuvant for Bupivacaine Caudal Block in Pediatric Open Appendectomy Under General Anesthesia

Recruiting now · Not applicable

Conditions studied: Appendectomy, Pediatric

In brief

This study aims to evaluate if adding dexmedetomidine to bupivacaine in a caudal block can provide longer and better quality pain relief for children after open appendectomy surgery. The study will also assess the effect of this combination on the quality of recovery, including the incidence of emergence delirium, and its overall safety profile.

Key facts

Study ID

NCT07088900

Run by

Ain Shams University

People needed

60

Starts

2025-08-01

Expected to finish

2026-07-30

Last updated by the study team

2026-05-06

Who can join

Age: 2 and older, up to 7. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• ASA (American Society of Anesthesiologists) physical status I or II.
• Legal guardian provides written informed consent. Exclusion Criteria
• Refusal of participation by the legal guardian.
• Known allergy or hypersensitivity to local anesthetics or dexmedetomidine.
• Coagulation disorder or receiving anticoagulant therapy.
• Active infection at or near the injection site.
• Significant anatomical abnormalities of the lumbosacral spine.
• Pre-existing neurological disorders, psychiatric disorders, or a history of convulsions.
• Anticipated surgery time of more than 2.5 hours.
• Patients with severe asthma or active wheezing.

Where it is running

• Ain Shams university hospitals — Cairo, Egypt (enrolling)

Full record on ClinicalTrials.gov

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