Dexamethasone in Prolonging the Duration of Spinal Anesthesia Among Pregnant Patients

Recruiting now · Phase 4 · Has a placebo group

Conditions studied: Spinal Anesthesia, Post Operative Analgesia

In brief

Lower segment C section is one of the most commonly performed surgeries worldwide. It is performed in spinal anesthesia. During Spinal Anesthesia a local anesthetic drug is administered in a space surrounding spinal cord and it blocks nerves originating from spinal cord providing both anesthesia and analgesia. This technique avoids harmful exposure of drugs to the baby inside the womb of mother. However this technique provides anesthesia and analgesia of limited duration which can be prolonged by addition of drugs to patient management regimen. One such drug is Dexamethasone which is a steroid commonly administered in the peri-operative period.

Key facts

Study ID

NCT07088146

Run by

Rawalpindi Medical College

People needed

110

Starts

2025-07-20

Expected to finish

2025-10-20

Last updated by the study team

2025-07-28

Who can join

Age: 16 and older, up to 40. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• American Society of Anesthesiologists (ASA) class: II and above.
• Elective Cesarean section under Spinal Anesthesia.

You may not qualify if…

• Gestational diabetes
• Body mass index >35 kg/m2
• Diabetes mellitus
• Adrenal insufficiency
• Chronically receiving steroids
• Allergic to study medications
• Sensory block level less than T4

Where it is running

• Benazir Bhutto Hospital Rawalpindi — Rawalpindi, Punjab Province, Pakistan (enrolling)

Full record on ClinicalTrials.gov

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