A Study to Learn About How a New Pneumococcal Vaccine Works in Adults
Running, not enrolling · Phase 1 · Has a placebo group
Conditions studied: Streptococcus Pneumoniae
In brief
The purpose of this study is to learn about the safety and tolerability of a pneumococcal vaccine in adults. Participants will receive either: * an experimental PG4 vaccine * a PG4 vaccine comparator * a standard 20vPnC vaccine comparator * placebo. A placebo does not have any medicine in it but looks just like the study medicine. Participants will take part in this study for up to 18 months depending on which group they are assigned to. During this time, the participants will receive up to two doses of study vaccine or comparator and take part in follow-up visits. At these clinic visits, participants will be asked if any side effects were experienced. The participants will also have to give blood samples during clinic visits.
Key facts
- Study ID
- NCT07086677
- Run by
- Pfizer
- People needed
- 380
- Starts
- 2025-07-22
- Expected to finish
- 2027-10-21
- Last updated by the study team
- 2026-06-22
Who can join
Age: 65 and older, up to 84. Sex: any. Healthy volunteers: accepted.
Where it is running
- Orange County Research Center — Lake Forest, California, United States
- Peninsula Research Associates — Rolling Hills Estates, California, United States
- Finlay Medical Research — Greenacres City, Florida, United States
- Indago Research & Health Center, Inc. — Miami Lakes, Florida, United States
- Johnson County Clinical Trials — Lenexa, Kansas, United States
- Bio-Kinetic Clinical Applications, LLC dba QPS-MO — Springfield, Missouri, United States
- Bio-Kinetic Clinical Applications, LLC dba QPS-MO-Screening and Recruitment Center — Springfield, Missouri, United States
- Bio-Kinetic Clinical Applications, LLC dba QPS-MO — Springfield, Missouri, United States
- Velocity Clinical Research, Omaha — Omaha, Nebraska, United States
- Upstate Global Health Institute — East Syracuse, New York, United States
- NYU Langone Health Vaccine Center — New York, New York, United States
- Duke Vaccine and Trials Unit — Durham, North Carolina, United States
- CTI Clinical Research Center — Cincinnati, Ohio, United States
- Headlands Horizons, LLC dba Headlands Research-Brownsville — Brownsville, Texas, United States
- Valley Regional Medical Center — Brownsville, Texas, United States
- LabCorp — Houston, Texas, United States
- IMA Clinical Research San Antonio — San Antonio, Texas, United States
- Dynamed Clinical Research, LP d/b/a DM Clinical Research — Tomball, Texas, United States
- J. Lewis Research, Inc. / Foothill Family Clinic — Salt Lake City, Utah, United States
- J. Lewis Research, Inc. / Foothill Family Clinic South — Salt Lake City, Utah, United States
Full record on ClinicalTrials.gov
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