Identifying Biomarkers for Endothelial Dysfunction in Women With Preeclampsia

Recruiting now · Not applicable

Conditions studied: Endothelial Function (FMD), Preeclampsia, Retinal Vessels

In brief

Every pregnancy has a major impact on a woman's heart and blood vessels due to changes required by the body to maintain proper blood flow between mother and foetus. When the placenta does not work properly, preeclampsia can occur. An important first symptom is high blood pressure. Women who have experienced preeclampsia are at higher risk of developing blood pressure and heart problems later on. Therefore, it is very important to detect changes in the blood vessel system so that they can be treated promptly and correctly. We aim to do this by using a new, non-invasive eye test that examines the blood vessels of the retina.

Key facts

Study ID

NCT07084727

Run by

University Hospital, Antwerp

People needed

60

Starts

2025-07-01

Expected to finish

2025-12-15

Last updated by the study team

2025-07-24

Who can join

Age: 18 and older, up to 40. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• at least 18 years old
• willing to undergo vascular assessments
• informed consent signed

You may not qualify if…

• Unwilling to provide informed consent
• Open-angle glaucoma
• Epilepsia
• (gestational) Diabetes
• Multiple pregnancies
• Fetal malformations
• Hypercholesterolemia
• Kidney disease
• Auto-immune disorders
• Connective tissue diseases

Where it is running

• Antwerp University Hospital — Edegem, Antwerp, Belgium (enrolling)

Full record on ClinicalTrials.gov

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