State of the Art Immediate Implant Placement in the Premaxilla
Recruiting now · Not applicable
Conditions studied: Bone Resorption
In brief
The goal of this clinical study is to learn how well immediate implant placement works in the front upper jaw (premaxilla) when using flapless guided surgery, hard and soft tissue augmentation, and immediate provisional crowns. It will also learn about the safety and esthetic results of this treatment approach. The main questions it aims to answer are: Primary: How much buccal bone thickness remains one year after implant placement 1mm below the implant shoulder? Secondary: * How do patients rate pain, healing, and esthetics after treatment? * Are there any complications over the course of five years? * How much buccal bone thickness remains one year after implant placement 3mm and 5mm below the implant shoulder? * Marginal bone loss at one-year and five-year follow-up? * Peri-implant health at one-year and five-year follow-up? * Soft tissue changes at one-year and five-year follow-up? Researchers will compare treatment results in patients with intact bone sockets to those with damaged (non-intact) sockets. Participants will: * Receive a dental implant and temporary crown on the same day as the tooth extraction * Undergo guided, flapless surgery with bone and soft tissue grafting * Take antibiotics and anti-inflammatories for 4 days after surgery * Visit the clinic at 1 week, 3 months, 1 year, and 5 years for follow-up exams * Have X-rays, digital scans, and photos taken to measure bone and soft tissue changes * Answer questions about pain and esthetic satisfaction
Key facts
- Study ID
- NCT07080710
- Run by
- University Ghent
- People needed
- 50
- Starts
- 2025-07-01
- Expected to finish
- 2032-02-01
- Last updated by the study team
- 2025-11-18
Who can join
Age: 20 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- At least 20 years old
- Good oral hygiene defined as full-mouth plaque score ≤ 25%
- Presence of one or more incisors, cuspids or premolars in the maxilla that need to be extracted for any reason with at least one neighboring tooth present
- At least 3 mm bone available at the apical or palatal aspect of the alveoli as assessed on a three-dimensional radiograph to ensure primary implant stability
- Written informed consent.
You may not qualify if…
- Pregnancy (will be explicitly asked)
- Systemic diseases
- Smoking; suppuration
- > 1 mm gingival asymmetry between the failing teeth and contralateral teeth
- Failing teeth outside the bone envelop as assessed on a three-dimensional radiograph
- Untreated periodontal disease; untreated caries lesions.
Where it is running
- Ghent University — Ghent, East Flanders, Belgium (enrolling)
- Bv Dr. Cosyn — Zottegem, East Flanders, Belgium (enrolling)
Full record on ClinicalTrials.gov
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