Prenatal Genetics Chatbot Trial: Prenatal GENEie

Starting soon · Not applicable

Conditions studied: Genetic Counseling

In brief

During pregnancy, all pregnant people are offered tests to look for genetic conditions in the baby. However, there isn't a standard way of giving this information to patients. Doctors have a lot of things to discuss during the first prenatal visit and don't always have time to explain genetics in detail. Also, not everyone has access to genetic counselors. Prenatal genetics can be confusing, especially for people who haven't had a lot of formal education or who speak languages other than English. There might be misunderstandings about what these tests can find and what their benefits or risks are for these tests. Mobile apps, like chatbots, could be a helpful way to give information about prenatal genetics. Almost everyone has a cell phone, and a chatbot can let people learn at their own speed and whenever they want. The goal of this study is to see if a chatbot app Prenatal GENEie can teach pregnant women about prenatal genetics, and compare the chatbot to talking with a genetic counselor in person. The study wants to answer these main questions: * Does the Prenatal GENEie help pregnant patients learn about prenatal genetics the same way as a meeting with a genetic counselor? * Can the Prenatal GENEie and in-person counseling both help people make decisions about whether they want prenatal genetic testing? The researchers will compare the chatbot Prenatal GENEie with in-person counseling to see if the chatbot teaches people about prenatal genetics in a similar way. Participants will: * Take a test to check what they already know about prenatal genetics prior to the intervention * Use the chatbot or have an in-person meeting with a genetic counselor * Take a test after using the chatbot or meeting with a counselor to see how much their knowledge has improved * Fill out a survey about how comfortable they feel with their decision to do or not do prenatal genetic testing

Key facts

Study ID

NCT07077707

Run by

Women and Infants Hospital of Rhode Island

People needed

1470

Starts

2026-01-01

Expected to finish

2029-03-31

Last updated by the study team

2025-07-28

Who can join

Age: 18 and older, up to 55. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• English or Spanish speaking with ability to read and write
• Gestational age <20 weeks
• Access to smartphone or tablet (through personal use or study)

You may not qualify if…

• Patients who have already had genetic counseling related to current pregnancy
• h/o trisomy, major fetal anomaly. or aneuploidy in previous pregnancy
• Parent with Robertsonian translocation
• Twins, vanishing twin, multi-gestation pregnancy
• Fetal anomaly noted in early pregnancy
• In- vitro fertilization with pre-implantation genetic testing (PGT-A or PGT-M)

Where it is running

• Women & Infants Hospital of Rhode Island — Providence, Rhode Island, United States

Full record on ClinicalTrials.gov

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