Breast Cancer Screening Adherence for Women at Moderate Risk for Breast Cancer
Recruiting now
Conditions studied: Breast Carcinoma
In brief
This study assesses breast cancer screening adherence for women at moderately increased risk for developing breast cancer based on gene mutation status or empiric risk model estimates. It also seeks to determine facilitators and barriers to screening.
Key facts
- Study ID
- NCT07076147
- Run by
- University of Southern California
- People needed
- 150
- Starts
- 2025-06-02
- Expected to finish
- 2028-06-02
- Last updated by the study team
- 2026-06-01
Who can join
Age: 30 and older, up to 75. Sex: female. Healthy volunteers: accepted.
You may qualify if…
- * >= 30 years
- =< 75 years
- Women with either:
- Genetic test results showing moderately increased breast cancer risk due to a pathogenic/likely pathogenic variant in ATM, CHEK2, BARD1, RAD51C, or RAD51D (Mutation carrier group) OR
- Calculated lifetime breast cancer risk estimates between 20% and 40% according to the Tyrer-Cuzick V8.0B empiric risk model (Empiric risk group)
- Patients provided breast cancer risk assessments by genetic counselors at USC Norris or LA General Hospital beginning in 2021 and at least 12 months ago
- Women recommended to undergo annual breast MRI and/or annual mammogram beginning at the time of their genetic counseling risk assessment
- English or Spanish speaking patients
You may not qualify if…
- * History of breast cancer before genetic counseling at University of Southern California (USC)
- Any metastatic cancer diagnosis at time of genetic counseling risk assessment
- Deceased
- Patient underwent a risk reducing mastectomy before their genetic counseling risk assessment
Where it is running
- Los Angeles General Medical Center — Los Angeles, California, United States (enrolling)
- USC / Norris Comprehensive Cancer Center — Los Angeles, California, United States (enrolling)
Full record on ClinicalTrials.gov
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