Cognitive-Motor Exergame Training in Frail Adults
Recruiting now · Not applicable
Conditions studied: Aging, Frailty
In brief
This international multicentre pragmatic randomized controlled trial (RCT) aims to evaluate the effectiveness of personalized, home-based cognitive-motor training using exergames in improving cognitive and motor functions in frail adults. A total of 344 frail participants from five European countries will be enrolled. Participants in the intervention group will engage in a personalized exergame program, while the control group will follow the Otago Exercise Program. Both groups will undergo 12 weeks of training. The primary outcome is balance, a critical component of functional independence and fall prevention, and a common denominator affected in both physical and cognitive frailty. Secondary outcomes including cognitive and motor fall-risk factors, fall incidence, cost-effectiveness, and psychosocial outcomes.
Key facts
- Study ID
- NCT07074639
- Run by
- Eleftheria Giannouli
- People needed
- 344
- Starts
- 2025-06-16
- Expected to finish
- 2027-05-31
- Last updated by the study team
- 2025-07-20
Who can join
Age: 50 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- 50 years and older
- Fried Frailty Phenotype score 3 or higher and/or MoCA score between 10-25
- Must be able to give informed consent
- Access to internet and a TV/large screen at home
You may not qualify if…
- Mobility limitations (e.g., severe arthritis or lower extremity amputation)
- Cognitive limitations (e.g., advanced Alzheimer's disease, frontotemporal/Lewy body/vascular dementia)
- Sensory limitations (e.g., color-blindness, complete hearing loss and neuropathy causing significant loss of sensation)
- Psychiatric limitations (e.g., acute, or uncontrolled affective disorders)
- Comorbidities that would impair their ability to engage in the training
- Simultaneous participation in other clinical trials/intervention studies
- Inability to understand game instructions and play the games safely, based on judgement of a therapist
Where it is running
- Institute of Human Movement Sciences and Sport, ETH Zürich — Zurich, Switzerland (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.