Effects of Intermittent Theta Burst Stimulation (iTBS) on Motor Recovery of Lower Extremity in Chronic Stroke Patients

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Stroke, Hemiparesis After Stroke, Chronic Stroke Patients, Hemiplegia, Ambulatory Difficulty

In brief

This study aims to evaluate the effects and clinical feasibility of non-invasive brain stimulation protocols, specifically intermittent Theta Burst Stimulation, as part of rehabilitation interventions for motor recovery of lower extremity in the chronic phase after stroke. It also seeks to explore the underlying mechanisms by investigating changes of functional and structural brain networks.

Key facts

Study ID

NCT07073235

Run by

Danderyd Hospital

People needed

56

Starts

2025-11-01

Expected to finish

2030-12-01

Last updated by the study team

2025-11-25

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age over 18
• Chronic stroke (>6 months)
• Residual hemiparesis FAC ≥3

You may not qualify if…

• Metal implants
• Epilepsy/seizures
• Pregnancy
• Claustrophobia (related to MRIs exams)
• Severe cognitive impairment
• Untreated or unstable depression/anxiety
• Other disabilities prohibiting intensive physical training

Where it is running

• Department of Rehabilitation Medicine, Danderyd Hospital, Danderyd, Stockholm 18288 — Stockholm, Sweden (enrolling)

Full record on ClinicalTrials.gov

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